Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 74 |
Sr. Scientist, Clinical Pharmacology
Cambridge, Massachusetts
The Sr. Scientist in Clinical Pharmacology position will support a rapidly expanding clinical portfolio of promising RNAi therapeutics. The candidate in this position should be well versed in PK and PD with strong ability to critically eval...
15h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview The Executive Director, HEOR is a critical Global Medical Affairs leader whose experience and expertise is key to leading the development and execution of HEOR strategies for Alnylam's portfolio of innovative products. This strateg...
15h
| Job Type | Full Time |
Field Reimbursement Director - Ohio Valley (Ohio, Western PA)
Cambridge, Massachusetts
Overview Reporting to the Field Reimbursement Director, Lead, the Field Reimbursement Director will optimize access to Alnylam products in his/her region by understanding and addressing reimbursement and patient access challenges. This posi...
21h
| Job Type | Full Time |
Senior Manager, Talent Acquisition, G&A
Cambridge, Massachusetts
Overview: The Senior Manager, Talent Acquisition, G&A is responsible for executing and supporting strategic recruiting initiatives that enable Alnylam to attract and hire high-quality talent across business units. This role partners closely...
21h
| Job Type | Full Time |
Senior Specialist, Artwork Management, Supply Chain
Cambridge, Massachusetts
Overview The Senior Artwork Specialist of Artwork Management will report to the Associate Director of Artwork Management within the Supply Chain Team. In this role, the primary responsibility for the Senior Artwork Specialist will be to dev...
21h
| Job Type | Full Time |
Manager, GxP Vendor/Supplier Audits
Cambridge, Massachusetts
Overview The Manager, GxP Vendor/Supplier Audits, is responsible for managing the global GxP (GMP, GDP, GCP, GLP, and GPV) vendor and supplier audit program. This role ensures external partners meet applicable regulatory requirements and in...
6d
| Job Type | Full Time |
Sr Director, Infrastructure & Operations
Cambridge, Massachusetts
Alnylam Pharmaceuticals, a distinguished and fast-growing biotech company, is in search of a Senior Director of IT Infrastructure. The role requires leadership and expertise in managing data centers, cloud platforms, networking systems, and...
6d
| Job Type | Full Time |
Quality Control Analyst II, Raw Materials
Cambridge, Massachusetts
Overview The Quality Control Raw Materials (QCRM) Analyst II plays a role in supporting the department's efforts to maintain the highest standards of quality and compliance from development through to commercialization. This includes testin...
6d
| Job Type | Full Time |
Senior Associate Scientist, Bioinformatics
Cambridge, Massachusetts
Overview: With six commercially approved RNAi therapeutics, Alnylam is at the forefront of gene silencing. Our success is built upon a rational, sequence-based approach to drug design driven by predictive models and high-throughput data gen...
6d
| Job Type | Full Time |
Senior Digital Manager, Corporate Brand and Creative
Cambridge, Massachusetts
Sr. Digital Manager, Corporate Brand and Creative Summary: Reporting to the Sr. Director, Global Head of Corporate Brand and Creative, the Sr. Digital Manager will have the opportunity to be part of a growing global team developing digital,...
6d
| Job Type | Full Time |