Executive Director, US TTR Field Medical

The Executive Director, Field Medical Affairs - US TTR, will serve as the senior-most leader of the U.S. Field Medical team, overseeing both the Medical Science Liaison (MSL) and Health Systems Medical Outcomes Liaison (MOSL) teams. This elevated role reflects our commitment to delivering integrated, high-impact field engagement across scientific leaders and healthcare system stakeholders.

This individual will be responsible for shaping and executing a unified, insight-driven comprehensive field strategy that supports the entire U.S. TTR portfolio. A central responsibility includes leading the development and execution of the overarching U.S. KOL and Health Systems Engagement Plan, in close collaboration with Medical Directors, Strategic Accounts and Market Access colleagues.

The Executive Director will also be accountable for leading, developing, and coaching the national Field Director team, fostering a high-performance, collaborative, and strategically aligned field force.

This position is a US-Field based position.

Key Responsibilities:

Strategic Field Medical Leadership

• Serve as the senior field leader for the U.S. TTR franchise, responsible for setting the vision and direction of the MSL and MOSL teams.
• Lead the design and execution of the integrated U.S. KOL and Health Systems Engagement Plan, ensuring coordinated and insight-driven interactions across academic leaders, community HCPs and IDN clinical executives.
• Partner with U.S. Medical Affairs, Global Medical, Commercial, Strategic Accounts and Market Access to ensure alignment of field activities with medical strategy and business priorities.
• Ensure high-quality scientific exchange, insight generation, and evidence-based support for healthcare decision-makers across all phases of the product lifecycle.

Field Director Team Leadership & Development

• Directly manage the national Field Director team, providing leadership coaching, strategic guidance, and performance management.
• Establish and monitor clear KPIs for field team performance, medical impact, stakeholder engagement, and insight generation.
• Drive a culture of collaboration, scientific rigor, accountability, and development across all levels of the field organization.
• Lead succession planning and talent development, ensuring the field leadership bench is prepared to scale with the needs of the business.

Cross-functional Engagement & Medical Affairs Integration

• Serve as a key member of the U.S. Medical Affairs Leadership Team, ensuring field medical strategy is tightly integrated with in-house efforts.
• Collaborate with Medical Directors to ensure alignment of scientific content and engagement planning.
• Partner with cross functional colleagues to ensure integration of the MOSLs in organized customer strategy and population health discussions.
• Ensure compliance with corporate policies and applicable regulatory requirements across all field activities.

Qualifications:

• Advanced degree required: PharmD, MD, or PhD.
• 15+ years of experience in the pharmaceutical/biotech industry, with a proven track second second-line field medical leadership (e.g., managing Field Directors or national teams) in a US medical affairs organization.
• Demonstrated success leading large, complex field organizations in the U.S. and in house US medical affairs experience.
• Strong track record of developing and operationalizing strategic engagement plans with KOLs and organized healthcare systems.
• Experience working cross-functionally within matrixed organizations, including in-house Medical Affairs strategic accounts, marketing, and Market Access.
• Deep understanding of the U.S. healthcare landscape, payer systems, and the evolving role of field medical in supporting value-based care.
• Strong communicator with executive presence and the ability to influence at all levels.
• Committed to scientific integrity, team development, and patient impact.

U.S. Pay Range

$287,300.00 - $388,700.00

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers

AboutAlnylam

We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.