Process Development Scientist

Process Development Scientist

Department of Laboratory Medicine

University of California, San Francisco

The Department of Laboratory Medicine at the University of California, San Francisco(UCSF) is seeking a motivated Process Development Scientist to join our Investigational Cellular Therapy (ICT) group (https://celltherapy.ucsf.edu/).The ICT program aims to accelerate the development and delivery of promising new cell and gene therapies targeting cancer, autoimmunity, infectious disease, and inherited hematologic and immune disorders. ICT has established collaborations with UCSF research groups and a variety of academic and industrial partners to develop new cell and gene therapy technologies, platforms, and products.

The successful candidate will lead cellular engineering activities within a highly skilled process develoment team, and collaborate closely with partner functions such as pre-clinical research, GMP manufacturing, analytical development, quality control, quality assurance, operations/facilities, and regulatory affairs to advance pipeline programs.

Key Responsibilities:

• Design and execute complex process development efforts using genomic and epigenomic engineering tools and platforms.
• Analyze, interpret, organize, and present data to internal and external groups in clear and concise manner.
• Author and review experimental proposals, SOPs, and technical reports for scientific publications and regulatory filings.
• Ensure data integrity, maintain laboratory record and prepare protocols and reports in a GMP-compliant manner.
• Work closely with internal and external partners to support technology transfers and implementation of new process technologies.
• Collaborate with and participate in teams to facilitate IND-enabling studies.
• Participate in GMP manufacturing campaigns for in-house products.

Scientific independence and attention to detail are critical to success in this position. The candidate will have the opportunity to contribute to scientific publications.

Required Qualifications:

• Associate Specialist- A master's degree (or equivalent degree) in Immunology, Biological Sciences, Biomedical Engineering, or a related field with a minimum of three years of relevant experience OR five to ten years of research experience.
  
  
• Full Specialist- A terminal degree (or equivalent degree) in Immunology, Biological Sciences, Biomedical Engineering, or related field or ten or more years of relevant experience.
• Working knowledge of basic scientific principles and methods in order to independently design and perform experiments of moderate scope and complexity.
• Hands-on experience with aseptic tissue culture techniques and flow cytometry.
• Organizational abilities and decision-making to prioritize work assignments.
• Effective written and verbal communication skills with internal and external collaborators.
• Ability to work in a collaborative manner, to assist in identifying any challenges or barriers.
• Candidates must meet the required qualifications at the time of appointment. Application materials must state qualifications (or if pending) upon submission.

Preferred Qualifications:

• Associate/ Full Specialist- A PhD
• Experience with genome editing techniques (e.g. CRISPR/Cas9 editing, base editing, prime editing, etc.)
• Knowledge of GMP manufacturing and regulations and practical experience in GMP operations.
• Experience in both process development and manufacturing environments for cell therapies.

Please apply online at https://aprecruit.ucsf.edu/JPF05317, with a CV, cover letter, and three references.

See Table 24B for the salary range for this position. A reasonable estimate for this position is $73,000-$188,200.

• 3 required (contact information only)

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct, are currently being investigated for misconduct, left a position during an investigation for alleged misconduct, or have filed an appeal with a previous employer.

* "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.

* UC Sexual Violence and Sexual Harassment Policy: https://policy.ucop.edu/doc/4000385/SVSH

* UC Anti-Discrimination Policy for Employees, Students and Third Parties: https://policy.ucop.edu/doc/1001004/Anti-Discrimination

* APM - 035: Affirmative Action and Nondiscrimination in Employment: https://www.ucop.edu/academic-personnel-programs/_files/apm/apm-035.pdf