Researcher 2 Medical School

Summary of Position:

Responsible for assisting in the training of new laboratory member and coordinating the successful operation of the mouse core. Conducting a variety of techniques in animal experimentation and molecular biology. Contribute to mouse colony organization and maintenance, using our laboratory's mouse cloud database to create specimen labels, archiving biological samples, supply ordering, molecular biology techniques including immunoblotting and qRT-PCR, animal necropsies, tissue preservation, shipment of biological samples and recording healthspan data in the database. Continuing self-motivated education in aging research is expected.

Essential and other Functions:

50% Animal Experimentation
Managing production of experimental animals for the needs of all iBAM members. Coordinate and lead animal tissue dissections for efficient sample collection for experimental needs. Animal husbandry, mouse colony management, collect and record data collected on live animals, mouse necropsies, collection and preservation of biological samples, performs IVIS imaging, dosing mice for drug studies, communicates with RAR veterinary staff concerning animal health cases, facilitates animal transfers, monitors health of experimental animals.

25% Sample and Data Management
Sample and Data Management: Using the lab's unique colony management database, create animal identifiers and cage cards, prepare necropsy reports and labels for biologic samples, archive samples in the tissue bank and ship biological samples to collaborators, maintain up to date records of culling and anesthesia logs.

10% Cellular and Molecular biology
Prepare tissue lysates, isolate RNA and protein, quantitate nucleic acids and protein levels, perform qRT-PCR, PCR genotyping, nucleic acid and protein electrophoresis, prepare and refresh cell culture media. Establishing and maintaining mouse embryonic fibroblasts and culture of neuronal cell lines for functional assays.

15% Supervision:
Training new lab staff and on IVIS, mouse colony management, animal husbandry and tissue collection techniques, delegates colony management responsibilities.

All required qualifications must be documented on application materials

Required Qualifications:

• BS/BA in a biomedical discipline and 1 year of experience, or a combination of related education and work experience to equal 5 years.
• Experience working with mice or similar model organisms.
• Mouse colony management or similar experience in managing large, complex projects.
• Strong interest in gaining an understanding of DNA damage, DNA repair and genome instability disorders.
• Strong ability to work with coworkers, colleagues, and collaborators to reach goals in a timely and efficient manner.
• Must have strong problem-solving skills, an ability to multitask and to work independently and as a group.

Preferred Qualifications:

• Applicants should have an interest in health sciences and interest in working with laboratory animals.

Our research program is focused on investigating the underlying causes of aging. We use mouse models extensively, employing both genetic and pharmacologic approaches to interrogate mechanisms of aging. Aging is investigated in vivo by measuring senescence, frailty, organ function and behavior. The candidate will join an exciting research environment in the Department of Biochemistry, Molecular Biology, and Biophysics and the Institute on the Biology of Aging and Metabolism at the University of Minnesota Twin Cities. The position offers exceptional training in animal physiology, aging, age-related disease and pre-clinical testing of drugs.

Working at the University

At the University of Minnesota, you'll find a flexible work environment and supportive colleagues who are interested in lifelong learning. We prioritize work-life balance, allowing you to invest in the future of your career and in your life outside of work.

The University also offers a comprehensive benefits package that includes:

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Scholarship
• Low-cost medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and employer-paid life insurance
• Employee wellbeing program
• Excellent retirement plans with employer contribution
• Public Service Loan Forgiveness (PSLF) opportunity
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost
• Employee Transit Pass with free or reduced rates in the Twin Cities metro area

Please visit the Office of Human Resources website for more information regarding benefits.

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-UOHR (8647).

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America's Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022).