Position Title: Research Scientist, Oncology Drug Discovery
Work Location: San Diego, CA 92121
Assignment Duration: 6 Months
Work Arrangement: Onsite (laboratory environment)
Position Summary:
- The Organization's Oncology Drug Discovery aims to discover transformative cancer medicines by combining patient need, deep target biology, and the right therapeutic modalities.
- Its strategy emphasizes disease-area leadership, foundational cancer biology, and tailoring modalities to the specific patient, biology, and target.
Background & Context:
- Translational insights, advanced technologies, and strong scientific collaboration are central to accelerating breakthroughs and maximizing patient impact.
- We are seeking a highly motivated research scientist to join a collaborative, multidisciplinary team focused on discovering and advancing innovative therapies for cancer patients.
- The successful candidate will design and execute rigorous experiments, generate decision-enabling data, and translate findings into testable hypotheses.
- This role offers the opportunity to work across discovery disciplines and contribute directly to oncology programs from target validation to drug discovery.
- This is a temporary position expected to last approximately six months.
Key Responsibilities:
- Design, execute, analyze, and document experiments that address key scientific questions in oncology drug discovery.
- Develop and apply relevant cellular, molecular, biochemical, and translational assays to evaluate targets, mechanisms of action, biomarkers, and therapeutic response.
- Operate, optimize, and troubleshoot workflows utilizing automated laboratory instruments to support scalable, reproducible data generation.
- Work closely with colleagues in biology, chemistry, data science, pharmacology, biomarker research, and translational medicine to advance project objectives.
- Generate high-quality, reproducible data and communicate conclusions, limitations, and recommended next steps at project-team meetings and broader scientific forums.
- Contribute to study strategy, experimental prioritization, and data-driven project decisions.
- Maintain current knowledge of cancer biology, and emerging therapeutic modalities within induced proximity.
- Promote a culture of scientific rigor, collaboration, inclusion, and continuous learning.
Qualification & Experience:
- BS in molecular biology, cell biology, biochemistry, or a related discipline.
- At least two years of wet-lab experience in an industry setting.
- Demonstrated expertise in mammalian cell culture and one or more areas such as genetic perturbation, protein biology, flow cytometry, or quantitative cellular assays.
- Strong experimental design, data analysis, troubleshooting, and scientific reasoning skills.
- Record of scientific achievement demonstrated through publications, presentations, or other meaningful contributions to research programs.
- Ability to work effectively in a matrixed, team-oriented environment and communicate with colleagues from diverse scientific backgrounds.
- Experience supporting oncology drug-discovery programs in an industry setting.
- Proficiency with automation to execute high-throughput cellular assays.
- Demonstrated contributions to low-molecular-weight drug discovery programs.
- Knowledge of tumor dependencies, resistance mechanisms and/or biomarker discovery.
- Experience with CRISPR-based approaches and engineered cellular models.
- Familiarity with statistical analysis, data visualization, and electronic laboratory documentation.
- Ability to manage multiple priorities, adapt to new scientific findings, and deliver against project timelines.
Working Conditions & Physical Demands:
- This position may require routine work in a laboratory environment and adherence to applicable safety, quality, and compliance standards.
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