Basic Science Research Associate - Pharmacology - 139273

The UCSD Department of Pharmacology is one of two basic science units in the School of Medicine where world-class researchers investigate the molecular basis of human diseases. The faculty are internationally renowned for their strength in elucidating basic cellular and molecular mechanisms of signal transduction that lead to innovative drug target identification and ultimately to drug discovery. The faculty also play a major role in medical and graduate student training, providing educational and programmatic offerings that span several disciplines, and provide diversity to meet the interests of a broad spectrum of students and scholars. More than one hundred trainees at the graduate student and postdoctoral level, as well as a staff of more than 50 research technicians and department administrators interact closely with the faculty. The diverse mix of ages, backgrounds, and talents creates a robust work environment with challenging career opportunities and a commitment to continued growth potential. We constantly seek to recruit highly motivated, technologically-advanced and interested individuals to become a part of our dynamic exploratory research and educational environment.

Under supervision, incumbent will assist lab members with standard experimental research techniques, cell culture, live cell imaging, and data analysis. Incumbent will assist with maintenance of mouse breeding colonies and perform laboratory maintenance duties including ordering supplies, making buffers, and handling reagent requests. Incumbent will oversee undergraduate helper in making buffers. Incumbent must interact easily with faculty, postdoctoral scholars, students, and research technicians in a large laboratory.

• Theoretical knowledge of chemistry, biochemistry or biology.

• Knowledge and experience in basic laboratory procedures and equipment, including sterile techniques, preparation of buffers and media, cell culture, PCR, plasmid preps, and protein analysis and purification.

• Ability to maintain careful, legible and well-organized laboratory notes.

• Ability to follow basic research protocols and to understand and execute both written and verbal instructions and tasks on schedule.

• Experience with performing protein assays and protein gel electrophoresis.

• Knowledge and understanding of laboratory safety and ability to work carefully with potentially harmful agents.

• Tact and diplomacy to interact with a variety of individuals including faculty, staff, students and foreign scholars.

• Willingness to learn new techniques.

• Attention to protocol and details.

• Ability to work well with others; take orders and explain protocols to others.

• Ability to work independently and cooperatively.

• Manual dexterity to perform experiments and manipulate lab equipment.

• Experience with and skill in using computers.

• Experience with Western blots especially of tissue from animals.

• Knowledge of microscopy techniques.

• Knowledge and experience in basic animal room work, including maintaining and breeding mouse colonies.

• Knowledge of protein purification techniques.

• Experience with CRISPR/Cas9.

• Knowledge of kinases and phosphatases.

• Job offer is contingent upon satisfactory clearance based on Background Check results.

• Willingness to work evenings and weekends, if necessary.

• Willingness to work with rodents.

• Willingness to work with hazardous materials.

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If applicable, life-support certifications (BLS, NRP, ACLS, etc.) must include hands-on practice and in-person skills assessment; online-only certification is not acceptable.

UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team!

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Misconduct Disclosure Requirement: As a condition of employment, the final candidate who accepts an offer of employment will be required to disclose if they have been subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct; or have filed an appeal of a finding of substantiated misconduct with a previous employer.

a. "Misconduct" means any violation of the policies governing employee conduct at the applicant's previous place of employment, including, but not limited to, violations of policies prohibiting sexual harassment, sexual assault, or other forms of harassment, or discrimination, as defined by the employer. For reference, below are UC's policies addressing some forms of misconduct:

• UC Sexual Violence and Sexual Harassment Policy
• UC Anti-Discrimination Policy
• Abusive Conduct in the Workplace