Position Information
| Posting date |
04/09/2026 |
| Closing date |
|
| Open Until Filled |
Yes |
| Position Number |
1129576 |
| Position Title |
Research Assistant I (Wang Lab) |
| Hiring Range Minimum |
$20.00 |
| Hiring Range Maximum |
$23.00 |
| Union Type |
Not a Union Position |
| SEIU Level |
Not an SEIU Position |
| FLSA Status |
Non-Exempt |
| Employment Category |
Regular Full Time w/end date |
| Scheduled Months per Year |
12 |
| Scheduled Hours per Week |
40 |
| Schedule |
Monday - Friday, 8am - 5pm with flexibility for occasional weekends, evenings, or changes in hours, as driven by the research needs. |
| Location of Position |
Lebanon, NH |
| Remote Work Eligibility? |
Onsite only |
| Is this a term position? |
Yes |
| If yes, length of term in months. |
24 |
| Is this a grant funded position? |
Yes |
| Position Purpose |
The Wang Lab studies the mammalian
SWI/
SNF chromatin-remodeling complex, which has been found mutated in more than 25% of human cancers. Despite the prevalence of
SWI/
SNF mutations, their contributions to tumorigenesis remain unclear. The focus of the lab is to determine the roles of major
SWI/
SNF subunits in regulating protein complex assembly and to assess the impact of complex composition on chromatin targeting. We use a combination of biochemical, genomic, and epigenomic assays to understand the functions of these complexes using various model systems.
The Research Assistant I will set up and conduct a variety of laboratory tests and experiments in support of research studies directed at
SWI/
SNF chromatin remodeling complex by applying established methods, procedures, and techniques. |
| Description |
The Wang lab has an opening for a Research Assistant I in the Department of Molecular & Systems Biology at the Geisel School of Medicine at Dartmouth College.
We are looking for highly motivated individuals with an interest in both basic and translational biomedical research, particularly in cancer epigenetics. We welcome individuals with degrees in biology, biochemistry, genetics, bioinformatics, and/or computer science.
The Wang Lab studies the mammalian
SWI/
SNF chromatin-remodeling complex, which has been found mutated in more than 25% of human cancers. Despite the prevalence of
SWI/
SNF mutations, their contributions to tumorigenesis remain unclear. The focus of the lab is to determine the roles of major
SWI/
SNF subunits in regulating protein complex assembly and to assess the impact of complex composition on chromatin targeting. We use a combination of biochemical, genomic, and epigenomic assays to understand the functions of these complexes using various model systems.
The Research Assistant I will set up and conduct a variety of laboratory tests and experiments in support of research studies directed at
SWI/
SNF chromatin remodeling complex by applying established methods, procedures, and techniques. |
| Required Qualifications - Education and Yrs Exp |
Bachelors plus 1-2 year(s) of experience or equivalent combination of education and experience |
| Required Qualifications - Skills, Knowledge and Abilities |
Education:
- Bachelor's degree with a major in either biology, biochemistry, genetics, bioinformatics, and/or computer science, or the equivalent.
Experience:
- One year of relevant laboratory/ research experience.
- Honors Thesis/Project experience is required.
Skills and Knowledge:
- Competence in several laboratory methods, procedures, and techniques, as well as the equipment and instruments, e.g., Western Blot, Next Gen Sequencing.
- Ability to work independently and apply critical thinking and sound judgment.
- Good organizational and time management skills.
- Willingness to work with/be exposed to hazardous materials, such as infectious materials, and/or hazardous chemicals.
- Knowledge of computers and software applications.
- Knowledge of standard computer software packages for data analysis and presentation, and online literature search engines.
|
| Preferred Qualifications |
|
| Department Contact for Recruitment Inquiries |
Alicea Bursey |
| Department Contact Phone Number |
603-646-5221 |
| Department Contact for Cover Letter and Title |
Dr. Xiaofeng Wang |
| Department Contact's Phone Number |
|
| Equal Opportunity Employer |
Dartmouth College is an equal opportunity employer under federal law. We prohibit discrimination on the basis of race, color, religion, sex, age, national origin, sexual orientation, gender identity or expression, disability, veteran status, marital status, or any other legally protected status. Applications are welcome from all. |
| Background Check |
Employment in this position is contingent upon consent to and successful completion of a pre-employment background check, which may include a criminal background check, reference checks, verification of work history, conduct review, and verification of any required academic credentials, licenses, and/or certifications, with results acceptable to Dartmouth College. A criminal conviction will not automatically disqualify an applicant from employment. Background check information will be used in a confidential, non-discriminatory manner consistent with state and federal law. |
| Is driving a vehicle (e.g. Dartmouth vehicle or off road vehicle, rental car, personal car) an essential function of this job? |
Preferred, but not required |
| Special Instructions to Applicants |
This position is funded by a grant. Continuation is based upon available funds.
This position is a 24 month term position.
Dartmouth College has a Tobacco-Free Policy. Smoking and the use of tobacco-based products (including smokeless tobacco) are prohibited in all facilities, grounds, vehicles or other areas owned, operated or occupied by Dartmouth College with no exceptions. For details, please see our policy.
https://policies.dartmouth.edu/policy/tobacco-free-policy
|
| Additional Instructions |
|
| Quick Link |
https://searchjobs.dartmouth.edu/postings/85277 |
Key Accountabilities
| Description |
Experiments:
- Sets up and assists with research protocols and experiments under the general guidance of the principal investigators and other senior investigators in the laboratory; may have primary responsibility for independently setting up, performing, and troubleshooting experiments.
- Performs cell culture (routine passage, cell transfection/selection and plating for various downstream assays)
- Performs biochemical assays such as cell lysate preparation and Western blotting and sedimentation assay
- Performs Next-generation sequencing assays such as CUT&RUN, ATAC-seq, and library preparation
- Anticipates unexpected findings and assists in trouble-shoots techniques.
- Reports experimental results to the principal investigator and other senior laboratory personnel and assists in their analysis
- Collaborates with the Principal Investigator to investigate and develop modifications to techniques, and documents all new techniques developed in the laboratory.
- Adheres to laboratory safety requirements, including general and chemical/hazardous waste safety disposal methods
|
| Percentage Of Time |
80% |
| Description |
Records:
- Maintain careful records of research activities, observations, and analyses
- Collects and analyzes data resulting from experimentation/testing.
- Summarizes results and prepares progress reports for oral presentation at laboratory meetings.
- Contributes to the preparation of scientific manuscripts by drafting portions of the text, preparing graphs, tables, and charts, etc.
|
| Percentage Of Time |
10% |
| Description |
Laboratory:
- Assists with day-to-day laboratory care and housekeeping.
- Assists with the need for and orders all supplies and reagents needed for experiments.
- Assists in the maintenance of laboratory equipment and safety records, and in the preparation of routine reagents.
- Assists with monitoring laboratory equipment and instrument performance; obtains maintenance and repair as necessary.
- Instructs others in laboratory methods, procedures, and techniques and provides technical guidance and direction as required.
- Performs other duties as necessary.
|
| Percentage Of Time |
10% |
-
| -- |
Demonstrates professionalism and collegiality through actions, interactions, and communications with others appropriate to an environment that is welcoming to all. |
| -- |
Performs other duties as assigned. |
|