Senior Research Specialist

NextGen Precision Health

The Immunomodulation and Translational Research Program in NextGen Precision Health, University of Missouri, Columbia, MO, is seeking a Senior Research Specialist. The program has developed various novel biologics and targeted delivery biomaterial platforms, demonstrating efficacy in inducing tolerance to allogeneic bone marrow cells and islets for the treatment of diabetes. The applicant will play a key role in developing immunomodulatory concepts, providing both intellectual and technical contributions.

The Senior Research Specialist will conduct studies utilizing novel biologics to modulate the immune response, aiming to prevent cell, tissue, and solid organ graft rejection, as well as enhance cancer immunotherapy, in preclinical models.

Duties for this Position include:

1) generation and production of novel biologics which are the foundation of the program;

2) designing and conducting quality control of produced biologics and assessing immunomodulatory efficacy of various novel immune ligands as single agents or in combination for targeted indications (cancer and autoimmunity);

3) contributing generation of humanized mouse models for testing the efficacy of lead protocols for prevention and treatment of autoimmunity and cancer;

4) perform immune monitoring studies using multiparameter flow cytometry, qRT-PCR, immunohistochemistry, confocal microscopy, and in vitro assays for immune cell functional assessment;

5) analyze and organize data for detailed record keeping, grant and manuscript submissions;

6) supervising day-to-day laboratory operations, including ordering supplies, inventorying reagents, supplies and maintaining mice breeding colonies and equipment, and overseeing research lab maintenance and safety protocols;

7) mentoring and training graduate and undergraduate students, and technicians in experimental techniques, and data analysis.

Additional responsibilities include preparing standard operating procedures, quality control of research reagents, ordering, and organizing the antibody& ordered reagents inventory.
Successful candidates will have exceptional organizational and time management skills. They must demonstrate the following durable skills: collaboration, communication, critical thinking, mindfulness, growth mindset, fortitude, confidentiality, integrity, and a commitment to the university's values.

Monday - Friday, 8 am-5 pm

Bachelor's degree and at least 2 years of experience from which comparable knowledge and skills can be acquired is necessary.

PhD degree in the immunology field, and minimum of 2 years of basic and or translational immunology laboratory experience.

Salary Range: $52,915.20 - $68,161.60 per year

Grade: GGS 9E

University Title: Senior Research Specialist

Internal applicants can determine their University title by accessing the Talent Profile tile in myHR.

Resume and cover letter

Columbia offers small-town friendliness with big city features and a high quality of life for people of all ages and interests. Founded on education and known as an ideal college town, its location also makes it an attractive spot for businesses and travelers. Located on Interstate 70 and U.S. Highway 63, Columbia is right in the middle of the state and the nation. Just a couple hours' drive from St. Louis and Kansas City, Columbia is Boone County's largest population center offering big-city culture, activities, and resources with a low cost of living. Columbia is home to a variety of restaurants and entertainment venues and hosts more than a dozen festivals each year. If you want to grow your career, continue your education, raise a family, and retire, Columbia is a good place to be!

This position is eligible for University benefits. As part of your total compensation, the University offers a comprehensive benefits package, including medical, dental and vision plans, retirement, paid time off, short- and long-term disability, paid parental leave, paid caregiver leave, and educational fee discounts for all four UM System campuses. For additional information on University benefits, please visit the Faculty & Staff Benefits website at https://www.umsystem.edu/totalrewards/benefits.

Equal Employment Opportunity

The University of Missouri is an Equal Opportunity Employer.

To request ADA accommodations, please call the Director of Accessibility and ADA at 573-884-7278.