New 
Principal Applied Science Manager
 Microsoft | |
 United States, Washington, Redmond | |
 Oct 29, 2025 | |
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OverviewAre you passionate about applying cutting-edge science to solve real-world problems at scale? Do you thrive in environments where you work with massive datasets and advanced machine learning techniques? Are you excited by the challenge of building intelligent systems that process trillions of records to deliver impactful experiences for millions of users?At Microsoft AI, we are redefining what's possible with data and AI. We're seeking a Principal Applied Science Manager to help design and develop the next generation of big data and AI-driven capabilities. Microsoft's mission is to empower every person and every organization on the planet to achieve more. As employees we come together with a growth mindset, innovate to empower others, and collaborate to realize our shared goals. Each day we build on our values of respect, integrity, and accountability to create a culture of inclusion where everyone can thrive at work and beyond. Starting January 26, 2026, Microsoft AI (MAI) employees who live within a 50- mile commute of a designated Microsoft office in the U.S. or 25-mile commute of a non-U.S., country-specific location are expected to work from the office at least four days per week. This expectation is subject to local law and may vary by jurisdiction.
ResponsibilitiesDrive strategic impact by identifying and leading high-leverage data science and analytics initiatives across multiple teamsDrive model inference optimization and system integration to reduce cost, latency and system optimizationApply advanced statistical modeling, machine learning, andanalyticstechniques to tackle complex problems such as fraud/anomalydetection,opportunitiesandbusiness impactanalytics.Design E2E solutions and drive projects from concept to production in a fast-paced, dynamic environment. | |