Bioinformatics Engineer
 Brigham and Women's Hospital | |
 United States, Massachusetts, Boston | |
| 60 Fenwood Road (Show on map) | |
 Oct 21, 2025 | |
|
We are seeking a motivated Bioinformatics Engineer to join Brigham and Women's Hospital. The ideal candidate will have experience working with large, complex datasets, transforming them into analysis-ready formats, and leveraging high-performance computing for machine learning and statistical modeling. This role focuses on developing scalable pipelines to process real-world electronic health records (EHR) and clinical data, enabling data-driven discovery in collaboration with clinical and research teams-with the ultimate goal of advancing diagnostic technologies for low- and middle-income countries. This position is an excellent opportunity for someone with strong data analysis or computational experience who is eager to apply those skills to cutting-edge biological and clinical research.
Data Engineering & Analysis *Design and implement pipelines for processing large-scale electronic health records and clinical datasets *Develop automated data cleaning, validation, and quality control workflows *Build scalable data processing systems capable of handling multi-million record datasets *Create and maintain data transformation scripts for standardizing clinical data formats *Collaborate with clinical scientists to translate research questions into analytical workflows *Ensure all data processing activities comply with HIPAA, IRB protocols, and institutional data governance policies Machine Learning & AI Implementation *Develop and deploy machine learning models for clinical prediction and classification tasks *Implement feature engineering strategies specific to clinical and biomedical data *Build model validation frameworks appropriate for healthcare applications *Create automated model monitoring and performance evaluation systems *Stay current with ML/AI best practices in healthcare and regulatory requirements This position involves working with sensitive patient data in secure computing environments. The role requires collaboration with clinical researchers, IT teams, and regulatory compliance officers. Some projects may involve tight deadlines related to clinical studies or regulatory submissions. Education Bachelor's, Master's, or PhD in Bioinformatics, Computer Science, Bioengineering, Statistics, Mathematics, or a related quantitative field Can this role accept experience in lieu of a degree? Experience in bioinformatics engineering or other software engineering 1-2 years required Experience with large-scale data processing and analysis Understanding of statistical methods and experimental design principles Proficiency in Python for data transformation, analysis, and visualization Experience with distributed, parallel, or cloud computing environments Familiarity with machine learning tools (scikit-learn, PyTorch, or TensorFlow) Knowledge, Skills and Abilities - Strong interpersonal skills and ability to effectively interact with all levels of staff and external contacts. -Solid analytical, organization, and time management skills. -Strong analytical and problem-solving skills -Excellent communication and documentation habits -Ability to work independently and collaboratively across multidisciplinary teams -Familiarity with cloud-based and containerized computing environments -Knowledge of HIPAA compliance, PHI handling, and secure data environments -Understanding of EHR data structures and clinical coding systems (ICD-10, LOINC, etc.) -Experience with workflow management systems -Experience with data governance and reproducibility best practices -Commitment to data integrity, security, and reproducible research-Back-end and API development using programs such as Python, NodeJS, C#, Java, R, and/or Perl. Physical Requirements
The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. | |