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Histocompatibility Specialist - Per Diem

Children's Hospital of Philadelphia
$15.00 - $507.00 Hourly
United States, Pennsylvania, Philadelphia
Aug 14, 2025

SHIFT:

Any (United States of America)

Seeking Breakthrough Makers

Children's Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation.

At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care-and your career.

CHOP does not discriminate on the basis of race, color, sex, national origin, religion, or any other legally protected categories in any employment, training, or vendor decisions or programs. CHOP recognizes the critical importance of a workforce rich in varied backgrounds and experiences and engages in ongoing efforts to achieve that through equally varied and non-discriminatory means.

A Brief Overview
The Immunogenetics Clinical Laboratory is part of the Children's Hospital of Philadelphia Division of Genomics Diagnostics and the Department of Pathology & Laboratory Medicine. The Immunogenetics lab performs high complexity diagnostic testing supporting the Solid Organ, Hematopoietic Stem Cell Transplant Programs, and Disease Association testing of the Children's Hospital of Philadelphia as well as its Outreach clients. The Immunogenetics Clinical lab focuses on the role of Human Leukocyte Antigen (HLA) molecules and the Major Histocompatibility Complex (MHC) in autoimmunity and transplantation. We are interested in the detailed characterization of the MHC by high throughput DNA sequencing technologies and the identification of polymorphisms important for many HLA associated diseases, compatibility, and rejection processes in transplantation.

The Per Diem Histocompatibility Specialist works with Laboratory and Clinical Transplant staff on-call (evenings and/or weekends) to perform and report critical histocompatibility testing for deceased donor transplants. They demonstrate a solid understanding of testing methods, instrumentation, and software programs related to Histocompatibility and Immunogenetics.

What you will do

  • Accurately performs diagnostic tests, procedures, and data analysis of the highest complexity as assigned in HLA Typing and Solid Organ Testing (SOT)
  • Diagnostic tests include but are not limited to:
    Molecular HLA typing by NGS, RT-PCR, SSO, and SSP
    Luminex based HLA Class I and II Antibody Screening
    Flow Cytometry & CDC-AHG based crossmatching
    Virtual Crossmatch and Epitope analysis
  • Participates in on-call rotation (24/7/365) for deceased donor testing for Renal, Cardiac, and Lung programs
    Reports critical value results to Clinicians and Transplant Coordinators
    Maintains transplant immunology specific skill set to accurately evaluate when communication of problematic
    events requires consult with Director/Manager
    Initiates and affects problem solving in emergent situations
  • Maintains knowledge of lab regulations for ASHI, CAP, CLIA, State of PA, and standards of Joint Commission accreditation agencies with the ability to train, guide and support newer Histocompatibility Specialists
  • Participates in lab initiatives, and mandatory and additional education opportunities. Identifies and pursues technical learning needs
  • Maintains competency assessment as per the requirements of ASHI, CMS, state, Joint Commission and CAP
  • Collaborates with all members of the Transplant team by actively communicating and reporting pertinent patient care information and data in a comprehensive manner.
  • Takes initiative in problem-solving equipment failures and communicates unresolved issues to Technical Supervisor or Manager
  • Assists with the completion of quality records of reagents/instrumentation for technical area
  • Completes and records all appropriate quality control documentation timely and accurately
  • Activates troubleshooting procedures when necessary
  • Self-motivated to independently manage time effectively and prioritize tasks.
  • Maintains a safe environment within the Laboratory, following all policies and procedures for safety, hazardous materials, security, and emergency preparedness
  • Complies with personal protective equipment (PPE) and other laboratory and hospital safety standards 100% of the time
  • Responsibly controls and maintains inventory

On Call Schedule

  • Either:
  • Monday - Thursday: 12:30am-8:00am
  • Or Friday at 9:00pm - Monday at 8:00am

Education Qualifications

  • Bachelor's Degree Biology, Medical Technology, or another science-related field - Required

Experience Qualifications

  • At least six (6) months of clinical HLA Laboratory experience on-call - Required
  • At least one (1) year of clinical HLA Laboratory experience on-call - Preferred

Skills and Abilities

  • Exhibits the ability to work with computer programs and computer controlled equipment (Required proficiency)
  • Exhibits the ability to handle and interpret data, multitask, and maintains confidential material (Required proficiency)
  • Exhibits good laboratory technique and safety practices (Required proficiency)
  • Exhibits good communication, technical and organizational skills (Required proficiency)
  • Experience and/or training in multiple laboratory sections and high complexity testing (advanced tech skill inventory) (Required proficiency)
  • Exhibits the ability interpret scientific literature & regulatory compliance and apply to laboratory policy & procedure improvement or development (Preferred proficiency)

Licenses and Certifications

  • Certified Histocompatibility Technologist (CHT) - American College of
    Histocompatibility and
    Immunogenetics (ACHI) - - Preferred
  • Certified Histocompatibility Specialist (CHS) - American College of
    Histocompatibility and
    Immunogenetics (ACHI) - - Preferred

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must receive an annual influenza vaccine. Learn more.

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SALARY RANGE:

$15.00 - $507.00 Hourly

Salary ranges are shown for full-time jobs. If you're working part-time, your pay will be adjusted accordingly.

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At CHOP, we are committed to fair and transparent pay practices. Factors such as skills and experience could result in an offer above the salary range noted in this job posting. Click here for more information regarding CHOP's Compensation and Benefits.

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