Research Science Support Specialist - Mellon College of Science - Pittsburgh Supercomputing Center

Carnegie Mellon University is a private, global research university that stands among the world's most renowned education institutions. With ground-breaking brain science, path-breaking performances, creative start-ups, big data, big ambitions, hands-on learning, and a whole lot of robots, CMU doesn't imagine the future, we invent it. If you're passionate about joining a community that challenges the curious to deliver work that matters, your journey starts here!

The Mellon College of Science (MCS) is home to four departments and many programs and research centers that cross disciplines. We approach scientific problems from fresh angles using creative interdisciplinary approaches while drawing on our departmental strengths in the core sciences.

Our Pittsburgh Supercomputing Center (PSC) within MCS is seeking a Research Science Support Specialist. This position offers an exciting opportunity to collaborate with top researchers, contribute to impactful scientific applications, and help advance cutting-edge computing technologies.

Core Responsibilities:

• Utilize realistic, biologically accurate computer simulations to test the hypothesis that aging-related changes in active zone (AZ) protein density and distribution can predict both single AZ and whole synapse function at the neuromuscular junction (NMJ).
• Adapt and convert an existing, experimentally validated MCell simulation of mammalian NMJ AZs into Python for compatibility with MCell4.
• Integrate calcium-activated potassium channels into the python mouse NMJ AZ model to expand its physiological relevance.
• Systematically modify parameters such as the density and spatial distribution of voltage-gated calcium channels (VGCCs), the number of docked synaptic vesicles, and other key features to evaluate whether aging-associated alterations in AZ structure can account for synaptic functional outcomes observed in our collaborators' optical and electrophysiological data.
• Use results from these simulation experiments to elucidate the structural and functional remodeling of AZs during aging and its role in the progression of dynapenia. Insights gained will inform future efforts to target and potentially reverse specific age-related changes in synaptic architecture and function.

Adaptability, excellence, and passion are vital qualities within Carnegie Mellon University. We are in search of a team member who can effectively interact with a varied population of internal and external partners at a high level of integrity. We are looking for someone who shares our values and who will support the mission of the university through their work.

Qualifications:

• Bachelor's degree in neuroscience, physics, or related fields is required.
• Minimum 1-3 years of experience in Monte Carlo simulations.
• Strong programming skills in Python.
• Proficiency with Monte Carlo algorithms, reaction-diffusion, MCell and CellBlender.
• Familiarity with Physics Based Rendering.
• Experience with Linux.
• Excellent communication, teamwork, and creative problem-solving abilities.
• A combination of education and relevant experience from which comparable knowledge is demonstrated may be considered.

Preferred Qualifications:

• Advanced experience with Monte Carlo algorithms and MCell and CellBlender tools.
• Hands-on experience with Linux.
• Familiarity with Physics Based Rendering.

Requirements:

• Successful background check

Why Work With Us?

At PSC and Carnegie Mellon University, we are committed to excellence, innovation, and collaboration. You'll be part of a dynamic team advancing scientific discovery and technology. Flexibility, creativity, and cultural sensitivity are key attributes of our workplace.

Joining the CMU team opens the door to an array of exceptional benefits.

Benefits eligible employees enjoy a wide array of benefits including comprehensive medical, prescription, dental, and vision insurance as well as a generous retirement savings program with employer contributions. Unlock your potential with tuition benefits, take well-deserved breaks with ample paid time off and observed holidays, and rest easy with life and accidental death and disability insurance.

Additional perks include a free Pittsburgh Regional Transit bus pass, access to our Family Concierge Team to help navigate childcare needs, fitness center access, and much more!

For a comprehensive overview of the benefits available, explore our Benefits page.

At Carnegie Mellon, we value the whole package when extending offers of employment. Beyond credentials, we evaluate the role and responsibilities, your valuable work experience, and the knowledge gained through education and training. We appreciate your unique skills and the perspective you bring. Your journey with us is about more than just a job; it's about finding the perfect fit for your professional growth and personal aspirations.

Are you interested in an exciting opportunity with an exceptional organization?! Apply today!

Location

Job Function

Position Type

Full Time/Part time

Pay Basis

More Information: