Research Associate II, Cell Biology, Hematology Research

Who We Are

BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health.

Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities.

Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best - people with the right technical expertise and a relentless drive to solve real problems - and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we've produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options.

About Worldwide Research and Development

From research and discovery to post-market clinical development, our WWRD engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic diseases.

• Cell Culture: Maintain and culture cell lines and primary cells to perform highly technical cell-based assays to evaluate target biology.
• Assay Development: Develop and optimize cell-based models and assays to support pre-clinical programs, including pharmacokinetics, efficacy, safety, and mechanisms of action of novel therapeutics.
• Technical Troubleshooting: Proactively troubleshoot technical issues and recommend potential corrective actions.
• Data Management: Record and maintain accurate and up-to-date records of experimental procedures, data, and conclusions in electronic laboratory notebooks and databases.
• Collaboration: Work independently and as part of a team, presenting data and participating in discussions in group meetings, department meetings, and Early Development team meetings as necessary.
• Documentation: Prepare SOPs and data reports to support nonclinical and clinical programs and associated regulatory submissions.
• Lab Management: Share responsibility for lab management duties, including maintaining lab equipment and purchasing standard lab materials.

• Education: Bachelor's or Master's degree in Cell Biology, Molecular Biology, or a related field.
• Experience: 2-4 years of relevant laboratory experience, preferably in a pharmaceutical or biotechnology setting.
• Technical Skills: Proficiency in cell culture (experience with primary cells, HSCs and/or iPSCs is highly preferred), transduction, transfection, cell-based assays, nucleic acid and protein extraction, droplet-digital PCR, ELISA, and western blot.
• Analytical Skills: Ability to perform data analysis and interpretation, with experience in statistical analyses being a plus.
• Communication: Strong written and verbal communication skills, with the ability to present data and contribute to the preparation of research reports, study reports, manuscripts, and regulatory documents.
• Teamwork: Ability to work collaboratively in a team environment and contribute to the broader scientific community.

• Experience with gene editing techniques and high-content imaging.
• Familiarity with regulatory requirements and guidelines for nonclinical and clinical programs.

Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned.

Equal Opportunity Employer/Veterans/Disabled

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

• Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.