Assistant Project Scientist-Beleford Lab

The Department of Physiology & Membrane Biology at the University of California, Davis, School of Medicine, seeks to hire one, full time Assistant Project Scientist in Dr. Beleford's Lab . The Assistant Project Scientist will perform research functions in vascular biology and human genetics.

The Project Scientist makes significant and creative contributions to a research or creative project in their academic discipline. The appointee possesses the subject matter expertise and the creative energy necessary to function at a high level of competence. The appointee will participate in activities to increase, improve, or upgrade competency in vascular biology and human genetics. Appointees with Project Scientist series may engage in University and public service. They do not have teaching responsibilities. Although the Project Scientist is expected to work independently under the general guidance of an academic member with an independent research program (i.e., Professor, Professional Researcher, etc.), they are not required to develop an independent research program or reputation. The Project Scientist will carry out research or creative programs with supervision by an individual in an academic title that carries with it automatic Principal status. The Project Scientist does not usually serve as a Principal Investigator but may do so by exception.

The incumbent will work under the supervision of Dr. Daniah Beleford and work cooperatively and collegially in a diverse environment.

MAJOR RESPONSIBILITIES

1. RESEARCH (90% EFFORT)

Research activity (70%)

This position requires creative contributions to and collaborative development of an active research program investigating topics relevant to the research area of vascular biology and human genetics methods and applications. Topics include subcellular fractionation, co-immunoprecipitation, proximity ligation assay, and site-directed mutagenesis in order to identify specific protein binding partners and amino acid residues that facilitate direct binding to other proteins in endothelial cells. They will provide assistance with generating and maintaining patient-derived fibroblast and induced pluripotent stem cell-derived endothelial cell lines. They will also assist with mouse studies and with maintaining mouse colonies. Finally, the APS will contribute to mentoring and training the lab's undergraduate, graduate, and junior specialist learners. They will provide input to data interpretation and conduct tracking, optimization of data acquisition and processing, data handling and analysis, and consulting with physician scientists on human application research.

The appointee will help to determine research goals in consultation with the Principal Investigator. The Project Scientist will design specific projects, including the selection of appropriate methods and techniques. In some cases, the appointee may supervise students or technicians regarding the technical aspects of the research, including methods development, trouble-shooting problems, interpreting results and planning follow-up experiments. The appointee collaborates with scientific colleagues in multi-disciplinary projects that include components falling within the appointee's area of expertise.

Publication (10%)

The appointee will publish research in peer-reviewed journals either independently or in collaboration with the PI or other members of the research team.

Grant Acquisition (10%)

The appointee will assist in writing proposals for funding from federal and state agencies and other funding organizations. The appointee will prepare and assist in the preparation of reports as required by granting agencies and prepare modifications of budgets and other grant components as needed.

2. PROFESSIONAL COMPETENCE AND ACTIVITY (5% EFFORT)

The candidate will participate in professional societies and conferences appropriate to their specific field of vascular biology and human genetics and will serve as a reviewer of research proposals, and scientific publications as appropriate.

The candidate will attend seminars to present research results and may give oral presentations to public and professional interest groups. When appropriate, the candidate may coordinate and/or give presentations at seminars and laboratory meeting.

3. UNIVERSITY AND PUBLIC SERVICE (5% EFFORT)

The appointee may undertake administrative tasks relevant to the smooth running of the laboratory enterprise as appropriate.

*This recruitment is conducted at the assistant rank. The resulting hire will be at the assistant rank regardless of the proposed appointee's qualifications.

Department: https://health.ucdavis.edu/physiology/

Lab: https://basicscience.ucdmc.ucdavis.edu/beleford-lab/

BASIC QUALIFICATIONS:

* Ph.D. or equivalent in Biomedical Sciences, Biochemistry, Molecular Biology, Cell Biology, Genomics, or Developmental Biology

* At least 4 years of experience in molecular and cell biology post terminal degree.

* Prior experience in mouse genetics, rodent handling, tissue culture, bioinformatics

* Evidence of academic accomplishment such as peer-reviewed publications and/or conference presentations.

PREFERRED QUALIFICATION:

• Proficient with specific technology or procedures such as basic molecular biology (PCR, cloning, plasmid prep, DNA and protein electrophoresis, etc.) and cell biology (tissue culture, transfection, etc.)
• Training in genomics and bioinformatics is preferred
• Training in molecular biology and cell biology preferred
• Experience with rodent handling preferred

• 3-5 required (contact information only)

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct, are currently being investigated for misconduct, left a position during an investigation for alleged misconduct, or have filed an appeal with a previous employer.

• "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.
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